Three key elements of bone regeneration
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Scaffolds Allograft chips or synthetic granules provide the osteoconductive elements to encourage the attachment of osteogenic precursor cells. Scaffold maintains volume of the defect site while anchoring surrounding cells. |
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Signals Proven osteoinductive properties of BMPs in demineralized bone stimulates the growth of new bone. |
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Cells Patient’s own osteoblasts, osteoclasts and mesenchymal stem cells integrate with the graft material. |
Osteoconduction provides the guidance, osteoinduction encourages he transformation of undifferentiated cells to active bone cells and osteogenesis, living osteoblasts within the graft material aid in the bone renovation process.