Which side of the Neomem® Xac amnion-chorion membrane is placed up and which down?

Is there an orientation to Neomem® Xac?

No, there is no orientation. Neomem® Xac amnion-chorion membrane, as well as all others we have seen in dentistry, do NOT have any orientation, as they are deepithelialized. They can be placed up or down, folded, and/or layered, without any concern.